Hijiri Takeuchi Selected Research

Methoxsalen (Oxsoralen)

7/2009	8-Methoxypsoralen, a potent human CYP2A6 inhibitor, inhibits lung adenocarcinoma development induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice.
9/2008	Establishment of a bioassay model for lung cancer chemoprevention initiated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female A/J mice.
3/2006	Dose dependent inhibitory effects of dietary 8-methoxypsoralen on NNK-induced lung tumorigenesis in female A/J mice.
11/2005	Mechanisms of chemopreventive effects of 8-methoxypsoralen against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung adenomas.
11/2003	Pretreatment with 8-methoxypsoralen, a potent human CYP2A6 inhibitor, strongly inhibits lung tumorigenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice.

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Hijiri Takeuchi Research Topics

Disease

10	Carcinogenesis 01/2010 - 05/2003
9	Neoplasms (Cancer) 01/2010 - 11/2003
6	Adenoma (Adenomas) 07/2009 - 05/2003
3	Body Weight (Weight, Body) 07/2009 - 11/2003
3	Adenocarcinoma 07/2009 - 05/2005
2	Hyperplasia 07/2009 - 09/2008
2	Neoplasm Metastasis (Metastasis) 12/2003 - 05/2003
2	Lymphatic Metastasis 12/2003 - 05/2003
2	Carcinoma (Carcinomatosis) 12/2003 - 05/2003
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2013
1	Lymphoma (Lymphomas) 01/2010
1	Leukemia 01/2010
1	Adenocarcinoma of Lung 07/2009
1	Lung Neoplasms (Lung Cancer) 09/2008
1	Colorectal Neoplasms (Colorectal Cancer) 05/2003

Drug/Important Bio-Agent (IBA)

5	Methoxsalen (Oxsoralen)FDA Link 07/2009 - 11/2003
5	4- (N- methyl- N- nitrosamino)- 1- (3- pyridyl)- 1- butanoneIBA 07/2009 - 11/2003
2	QuinoxalinesIBA 01/2010 - 09/2009
2	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 07/2009 - 11/2005
2	probasinIBA 06/2005 - 05/2005
2	Tumor Viral Antigens (Large T Antigen)IBA 06/2005 - 05/2005
2	Cyclin B1IBA 12/2003 - 05/2003
1	nedaplatinIBA 01/2013
1	Docetaxel (Taxotere)FDA Link 01/2013
1	Cytochrome P-450 CYP1A2 (CYP1A2)IBA 09/2009
1	AminesIBA 09/2009
1	LactoferrinIBA 02/2007
1	Messenger RNA (mRNA)IBA 03/2006
1	EnzymesIBA 03/2006
1	Corn Oil (Oil, Corn)IBA 03/2006
1	steroid hormone 7-alpha-hydroxylaseIBA 11/2005
1	Protein SIBA 11/2005
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 06/2005
1	nimesulide (Aulin)IBA 06/2005
1	Testosterone (Sustanon)FDA Link 06/2005
1	AndrogensIBA 06/2005
1	Estrogen Receptor Modulators (Antiestrogen)IBA 06/2005
1	Raloxifene Hydrochloride (Evista)FDA Link 06/2005
1	arctiinIBA 05/2005
1	Chromogranin AIBA 01/2005
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2005
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2005
1	SynaptophysinIBA 01/2005
1	Keratins (Keratin)IBA 01/2005
1	CytokinesIBA 01/2005
1	Cyclin EIBA 12/2003
1	Cyclin AIBA 12/2003
1	Cyclin G1IBA 05/2003
1	CyclinsIBA 05/2003

Therapy/Procedure

1	Chemoradiotherapy 01/2013
1	Chemoprevention 09/2008